G. Michael Felker  美国杜克大学医学院
    <International Circulation>: What makes a good biomarker?

  《国际循环》：一个好的生物标志物需要哪些条件？
    Prof. Felker: The first thing I would say is that it is not one size fits all. The question has to be asked， what do you need it for? Are you trying to make a diagnosis? Are you trying to understand prognosis? Are you trying to pick a treatment? What you want in a biomarker might be completely different depending on what your question is. A good analogy is that a biomarker is just a tool. When you reach into the toolbox， you need to know what it is you are trying to accomplish before you know which tool will be best for the job.

    Felker教授：首先我要说，并没有一个统一的标准。必须先回答这些问题：你需要它做什么？你要做出诊断吗？你要预测预后吗？你要选择治疗方法吗？这些问题的不同答案会让你对生物标志物的需求完全不同。打个比方，生物标志物只是一个工具。如果你打开工具箱，你需要知道你要做什么工作，然后才能知道做这项工作需要的最佳工具。