<International Circulation>:  Is there any particular mistake that you think people are making in biomarkers whether it is a mistake in using a biomarker in a certain way or whether it is using certain biomarkers that are redundant for example?

  《国际循环》：您认为，在生物标志物方面，人们是否犯了错误？错误是在哪方面，是用特定方法使用生物标记物，还是不必要的使用生物标记物？
     Prof. Felker:  I think a common mistake is expecting a biomarker to be the magical sorcerer’s stone that unlocks the key to the future. A biomarker is just a measurement. It is just additional information to be used in conjunction with what you already know from the patient history， physical examination， other tests that have been conducted， imaging and so on. There are all these domains of information that are coming into your decision making and biomarkers is just one of those which needs to be integrated with all these different factors into something that is going to help you decide what to do in a given situation. Sometimes， people will almost expect too much. Just because you BNP is high does not mean that you will need to follow this course of action; it tells you that you are at high risk， it tells you that you almost certainly have heart failure but it doesn’t tell you necessarily what to do.

    Felker教授：我认为一个常见的错误是期望生物标记物是巫师的魔法石，开启未来的钥匙。生物标记物仅仅是一个检测。它只是一种额外信息，而且要和患者的病史，体检，其他检查，影像学等所提供的信息相结合。对于医生作出决断来说，有如此多的信息来源，生物标志物只是其中之一，并且需要和各种不同的因素相结合，才能够帮助医生在某种情况下作出决断。有时候，人们对生物标志物期待的太多了。因为BNP升高并不意味着需要接受治疗，而只是提示在高危状态，只是告诉你几乎肯定有心力衰竭，但是却无法告诉你需要做什么。